As life expectancy increases, so does the incidence of disease. It is the major risk factor for age-related diseases. In response to this societal challenge, the search for new therapies has intensified and the need for good preclinical models is paramount. At CD BioSciences, we recognize the growing importance of understanding the complex mechanisms underlying aging-related diseases. Our comprehensive suite of aging-related disease model customization services enables clients to explore these critical areas.
Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's, are heavily influenced by aging. Our team of experts specializes in developing customized in vitro and in vivo models that faithfully recapitulate the hallmarks of these debilitating diseases, including but not limited to iPSCs-derived cells, rodents, non-human primates (NHPs), Caenorhabditis elegans, and yeasts. We help clients customize models to unravel the intricate interplay between aging and neurodegeneration. Our models incorporate genetic engineering, cellular biology, and biochemical analysis, allowing clients to investigate the complex pathways and mechanisms underlying these debilitating diseases.
Cardiovascular health is intrinsically linked to the aging process. CD BioSciences offers specialized services for the development of aging-related cardiovascular disease models, including models of atherosclerosis, hypertension, and heart failure (HF). We offer highly customized cell and animal models that faithfully recapitulate the complex pathophysiology of cardiovascular disease in aging. Our expertise in cellular senescence, vascular remodeling, and oxidative stress allows us to deliver customized solutions that accelerate the discovery of novel therapeutic strategies.
Age-related bone disorders pose a significant challenge to the aging population. At CD BioSciences, we are skilled in developing customized mouse, rat, and NHP models that mimic the complex pathophysiology of this disease. Our team of experts helps clients customize animal models to their specific requirements, determining strain selection, age at initiation, and induction methods. Furthermore, our experienced team will work closely with clients to assess the research goals, disease stages, and physiological relevance to recommend the optimal models. Our services enable clients to uncover innovative approaches to maintain skeletal health and prevent debilitating fractures.
The aging process can also profoundly impact respiratory function, leading to diseases like asthma and chronic obstructive pulmonary disease (COPD). We help clients customize models by selecting appropriate mouse strains that faithfully recapitulate the key features of aging lungs, allowing our clients to understand the mechanisms driving these diseases. We offer a wide range of customized mouse models, unveiling the roles of various signaling pathways and regulatory molecules in the aging process and airway functions.
At CD BioSciences, we are dedicated to offering our clients customized models of aging-related diseases. If you are interested in our services, please feel free to contact us or make an online inquiry.
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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
CD BioScience is a research service provider focused on aging research, specializing in providing research on aging mechanisms, preclinical drug discovery and development, and the development of healthcare and skincare products.
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