Aging is a significant risk factor for the development of cardiovascular diseases (CVD), which are among the leading causes of morbidity and mortality globally. The comprehension of the underpinned molecular mechanisms is the key to therapeutic advancements. Researchers have long sought to develop experimental models that can faithfully recapitulate the human manifestations of cardiovascular diseases. The availability of reliable experimental systems enables the screening and evaluation of potential therapeutic interventions using simple and reproducible techniques.
CD BioSciences has expertise in developing customized animal and cell models for the study of aging-related CVDs. Our team of seasoned specialists has established a reputation for delivering reliable results that enable our clients to push the boundaries of aging research.
Atherosclerosis is closely linked to the aging process. We offer customized animal and cell models that faithfully recapitulate the complex atherosclerosis pathophysiology, such as primary cell, rodent, rabbit, and porcine models. Our customized atherosclerosis models provide a powerful platform for high-throughput screening, mechanistic studies, and the evaluation of novel therapeutic interventions targeting atherosclerosis. Our experts work closely with clients to meticulously customize models that capture the hallmarks of atherosclerosis.
At CD BioSciences, our hypertension model customization services cater to the unique needs of aging research. We help clients customize nongenetic models, genetic rodent models, and large genetic animal models of hypertension. Our specialists can design and validate hypertensive models that consider aging-related changes in vascular function, sympathetic nervous system activity, and other key determinants of blood pressure regulation.
Leveraging various techniques, we help clients customize heart failure models that faithfully recapitulate the age-related changes in cardiac structure, function, and pathological remodeling. We offer a range of animal models of heart failure, such as rat, mouse, and rabbit models. Additionally, our experts can generate cell models of heart failure using cardiomyocytes and cardiac fibroblasts that mimic aging phenotypes, providing a comprehensive platform for investigating the pathogenesis of heart failure.
We offer a wide range of complementary services using customized models, including:
At CD BioSciences, we are committed to enabling our clients to push the boundaries of the research of aging-related CVD. If you are interested in our services, please feel free to contact us or make an online inquiry.
References
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
CD BioScience is a research service provider focused on aging research, specializing in providing research on aging mechanisms, preclinical drug discovery and development, and the development of healthcare and skincare products.
Copyright © 2024 CD BioSciences. All rights reserved.