Aging is a complex and multifaceted process that has been a focus of biological research for decades. Lifespan analysis is critical to the study of aging, offering insights into the genetic, environmental, and molecular factors that influence longevity. By utilizing a variety of model organisms, researchers can investigate the mechanisms underlying aging and develop interventions to promote healthy lifespan extension.
Fig. 1 The entire life of five organisms from fertilization to death, all scaled to the same length bar. (Azam S, et al., 2021)
CD BioSciences specializes in lifespan analysis in various model organisms. Each of our services offers unique advantages in the pursuit of aging research. We provide a series of services that contribute to the development of novel treatments for age-related diseases.
The nematode Caenorhabditis elegans (C. elegans) is one of the most widely used model organisms in aging research. We employ the traditional longitudinal method (TLM) and the replica set method (RSM) to analyze C. elegans lifespan. Our approach involves maintaining cohorts of C. elegans under controlled conditions and monitoring their survival from embryonic stages to adulthood. We offer a wide range of C. elegans strains, culture systems, and culture temperature options to meet the demands of clients' research.
With its short lifespan, well-established genetic tools, and wealth of available genomic data, Drosophila melanogaster (D. melanogaster) provides unparalleled models for lifespan research. Our team of experts tracks the survival, activity, and physiological changes of individual D. melanogaster, allowing our clients to identify key regulators of the aging process and develop novel strategies to promote healthy aging. We not only analyze individual lifespan data but also comparative analyses between various Drosophila strains or experimental conditions.
Leveraging the physiological and genetic similarities between rodents and humans, we help clients elucidate the mechanisms of aging and evaluate the efficacy of potential longevity-enhancing interventions. We provide lifespan analysis services for a range of rodent species, including short and long-lived species. Our trained technicians monitor rodents daily and record median lifespan, maximum lifespan, and survival data.
CD BioSciences employs a systematic approach to analyze zebrafish lifespan, from egg collection and fertilization to monitoring the lifecycle of zebrafish. Our experts observe zebrafish behavior, feeding, and growth rate, and record any changes or signs of aging. We also help clients take a deep dive into the multitude of factors that can affect zebrafish lifespan, such as genetic variants, environmental factors, and pharmacological interventions.
At CD BioSciences, we are committed to advancing the field of aging research and providing our clients with comprehensive and innovative lifespan analysis services. Leveraging the power of model organisms, our team of experts is dedicated to uncovering the fundamental mechanisms that govern longevity and developing novel strategies to enhance healthspan and promote healthy aging. If you are interested in our services, please feel free to contact us or make an online inquiry.
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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
CD BioScience is a contract research organization focused on aging research, specializing in providing research on aging mechanisms, preclinical drug discovery and development, and the development of healthcare and skincare products.
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