Rodent Lifespan Analysis Services

The study of aging is a complex and multifaceted field that seeks to unravel the mechanisms underlying senescence and longevity. Rodent models, particularly rats and mice, play a pivotal role in this research due to their genetic and physiological similarities to humans. Beyond traditional models, the order Rodentia includes several long-lived species, such as the naked mole-rat, beavers, porcupines, and certain squirrels, with lifespans exceeding 20 years. This diversity provides exciting opportunities for comparative aging studies.

Fig. 1 Lifespan of different rodent species. (Gorbunova V, et al., 2014)

CD BioSciences offers specialized rodent lifespan analysis services that cater to the needs of researchers investigating the mysteries of aging. We prioritize the reliability and reproducibility of our lifespan analyses.

Rodent Species for Which We Offer Lifespan Analysis

CD BioSciences provides lifespan analysis services for a range of rodent species, with a particular focus on the most commonly used models in aging research.

Our Rodent Lifespan Analysis Services

CD BioSciences offers a suite of services designed to provide a thorough analysis of rodent lifespan, from study design to data interpretation.

• Study design. Our experts work closely with clients to design studies that address specific research questions in the field of aging. We consider factors such as strain selection, environmental conditions, and pharmaceutical interventions.
• Monitoring and data collection. Our trained technicians monitor rodents daily and record survival data. Environmental parameters are strictly controlled to minimize external influences on lifespan. Based on our experience, reliable signs that we consider a rodent to be dying include but are not limited to, unresponsiveness to touch, failure to eat or drink, slow breathing, arching of the body, and sudden loss of weight.

Statistical Parameters of Rodent Lifespan

Median lifespan

We help clients measure the median lifespan, which is the age at which 50% of the population has died. It is a critical measure of the average lifespan and is sensitive to changes in survival due to pharmaceutical interventions or genetic modifications.

Maximum lifespan

Our experts assess the maximum lifespan that represents the oldest age reached by any individual in the study. It provides information on the potential upper limit of survival and is often of interest when studying interventions that may promote longevity.

Survival curves

Survival curves are graphical representations of the proportion of individuals surviving over time. CD BioSciences helps clients generate these curves to compare the lifespan of different groups and identify significant differences in survival patterns. We plot the survival curve using time as the X-axis and the proportion of surviving individuals as the Y-axis.

At CD BioSciences, our commitment to excellence in rodent lifespan analysis services enables researchers to delve deeper into the complexities of aging. If you are interested in our services, please feel free to contact us or make an online inquiry.

References

1. Gorbunova V, et al. Rodents for comparative aging studies: from mice to beavers. Age (Dordr), 2008, 30 (2-3): 111-9.
2. Gorbunova V, et al. Comparative genetics of longevity and cancer: insights from long-lived rodents. Nat Rev Genet, 2014, 15 (8): 531-40.