Custom Biospecimen Services for Aging Research
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Custom Biospecimen Services for Aging Research

As the global population ages, understanding the biological processes of aging becomes increasingly important for the development of effective therapeutics. The use of custom biospecimens enhances the relevance and applicability of research findings, ultimately facilitating the discovery of therapeutic strategies against aging and aging-related diseases. CD BioSciences offers comprehensive custom biospecimen services for aging research. Our services allow clients to efficiently acquire biospecimens and obtain analysis results that align with their specific requirements.

Histological analysis of biospecimens in aging research.

Our Custom Biospecimens for Aging Research

CD BioSciences offers a comprehensive selection of biospecimens from different species to meet the diverse research needs of our clients. Additionally, we specialize in providing aged biospecimens from animal models, facilitating advanced studies in aging research.

Species Biospecimen Types Applications
Rodent (mouse, rat) Serum, whole blood, brain, eyes, heart, muscle, lungs, liver, skin, kidney tissues, etc.
  • Investigating the role of genetic mutations in aging and aging-related diseases.
  • Analyzing the metabolic changes associated with aging and their implications for longevity.
  • Exploring the neurological aspects of aging, including the impact of age-related cognitive decline and neurodegenerative diseases.
  • Testing anti-aging drugs to improve lifespan.
  • Exploring aging-related molecular pathways.
NHP (macaques, baboons) Adipose, bone, brain, eye, heart, kidney, liver, lung, mammary, ovarian, muscle, serum, skin, stomach, uterus tissues, etc.
Zebrafish Whole organisms, clear embryos, heart tissue, retina, etc.
Caenorhabditis elegans Whole organisms, stem cells, tissue extracts, etc.
Drosophila melanogaster Whole organisms, brain tissue, intestines, etc.

Aging Analysis Services with Custom Biospecimens

Aging can be assessed through various parameters, including genetic markers, metabolic profiles, and physiological changes. CD BioSciences uses a variety of biospecimens to help clients assess aging comprehensively.

Our Services Services Details Technologies Available Biospecimens
Cell and histological analysis in aging research
  • Separation of young and old cells: We perform cell sorting using flow cytometry, which separates cells with distinct characteristics.
  • Identification of age-related structural changes: We examine cellular morphology and tissue architecture to identify age-related structural changes.
  • Identification of biomarkers of aging: We help clients identify specific markers of senescence in cells, such as the senescence-associated β-galactosidase (SA-β-gal).
Histopathology, immunohistochemistry (IHC), flow cytometry Tissue samples (e.g., brain, liver, muscle), cells
Multi-omics integration analysis in aging
  • Identification of proteomic markers of aging and longevity
  • Analysis of metabolic alterations in aging
  • Investigation of the relationship between cellular heterogeneity and aging
Genomics, transcriptomics, proteomics, single-cell omics, metabolomics Blood, tissue, and cells
DNA methylation analysis in aging
  • Prediction of DNA methylation-based age
  • Analysis of DNA methylation levels in blood, saliva, and skin samples.
Targeted bisulfite sequencing, reduced representation bisulfite sequencing (RRBS), whole genome bisulfite sequencing (WGBS), global DNA 5mC/5hmC measurement Blood, saliva, and skin
Telomere length analysis We offer reliable relative and absolute telomere length measurement services, providing valuable insights into the correlation between telomere length and aging processes. Telomere restriction fragment (TRF) analysis, quantitative polymerase chain reaction (qPCR), quantitative fluorescence in situ hybridization (Q-FISH) DNA, blood, saliva, fresh tissues, and cells

Anti-Aging Drug Development Services with Custom Biospecimens

CD BioSciences provides services focused on target discovery, mechanism of action studies, and drug efficacy evaluation, using custom biospecimens specifically for aging research.

Our Services Services Details Available Biospecimens
Identification of anti-aging targets Our experts use biospecimens to help clients conduct proteomics and metabolomics analyses to identify key targets in aging and aging-related diseases. Cells, tissue samples, whole organisms
Evaluation of anti-aging drug efficacy We help clients evaluate anti-aging drug efficacy using in vitro and in vivo assays. Our experts assess changes in cellular senescence, inflammation, and regenerative capacity. Cells, tissue samples, whole organisms

Custom biospecimens are essential for unraveling the complexities of aging and developing therapeutics to promote healthy aging. CD BioSciences offers customized solutions to help clients unravel biological aging and develop effective anti-aging therapeutics. If you are interested in our services, please feel free to contact us or make an online inquiry.

References

  1. Vaught JB, Henderson MK. Biological sample collection, processing, storage, and information management. IARC Sci Publ, 2011, (163): 23-42.
  2. Hartman V, et al. Biospecimen Complexity and the Evolution of Biobanks. Biopreserv Biobank, 2019, 17 (3): 264-270.
  3. Tollefsbol TO. Techniques for analysis of biological aging. Methods Mol Biol, 2007; 371: 1-7.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.