CAT. NO.: ABS-075
| Product Details | |
|---|---|
| Alternate Name | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecar boxamide dihydrochloride |
| CAS Number | 129830-38-2 |
| Molecular Formula | C14H21N3O.2HCl |
| Molecular Weight | 320.26 |
| Appearance | White soild |
| Purity | ≥99% by HPLC |
| Solubility | H2O (100 mM) or PBS (100 mM) |
| SMILES | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
| PubChem CID | 9901617 |
| Handling | Protect from air and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Selective inhibitor of the Rho-associated protein kinase p160ROCK. Ki values are 0.14, 26, 25 and >250 µM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase, respectively. Prevents apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem cells (hES) without affecting their pluripotency. | |
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