VCP Antibody

INQUIRY

CAT. NO.: AMA-0241

Product Details
Size	100 μL
Reactivity	Human, Mouse
Host	Rabbit
Source/Isotype	Rabbit IgG
Storage	Store at -20°C.
Purification	Affinity purified

Usage
Application	WB, IHC
Product Usage Information Dilution	Western Blotting (1:500-1:2000)

Background
Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase) or p97, is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is the mammalian homolog of Saccharomyces cerevisiae Cdc48, a protein essential for the completion of mitiosis in yeast. VCP is thought to be involved in a variety of membrane functions and in the regulation of the cell cycle. It associates with ubiquitinated IκB-αas well as with the 26S Proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IκB-α.

Background

Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase) or p97, is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is the mammalian homolog of Saccharomyces cerevisiae Cdc48, a protein essential for the completion of mitiosis in yeast. VCP is thought to be involved in a variety of membrane functions and in the regulation of the cell cycle. It associates with ubiquitinated IκB-αas well as with the 26S Proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IκB-α.

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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.