CAT. NO.: ABS-071
| Product Details | |
|---|---|
| Alternate Name | 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene |
| CAS Number | 109511-58-2 |
| Molecular Formula | C18H16N6S2 |
| Molecular Weight | 380.48 |
| Appearance | White to off-white solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>10 mg/mL) |
| SMILES | C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N |
| PubChem CID | 3006531 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC50 values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4. | |
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