CAT. NO.: ABH-027
Product Details | |
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Alternate Name | TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
CAS Number | 58880-19-6 |
Molecular Formula | C17H22N2O3 |
Molecular Weight | 302.4 |
Appearance | White solid |
Purity | ≥99% |
Solubility | DMSO (20 mg/mL) or EtOH (2 mg/mL) |
SMILES | CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C |
PubChem CID | 444732 |
Handling | Protect from air and moisture. |
Storage Conditions | -20°C |
Description | |
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Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis. |
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