Telomeres shorten progressively with age, and therefore telomere length can be used as a predictor to determine the lifespan of cells and organisms. Certain diets, behaviors, lifestyles, or substances may affect human health and longevity by accelerating telomere shortening and leading to accelerated aging or disease. To help researchers fully study telomere length and aging-related outcomes, CD BioSciences provides a technical platform for telomere length measurement and telomere-related research services.
We have a unique telomere length measurement technology and research system to explore aging and age-related diseases for telomere length analysis, providing services including basic measurement, comprehensive dynamic analysis, and assessment of factors affecting telomeres.
Telomere Length Measurement Services for Aging Research
We offer a comprehensive suite of telomere length measurement services tailored to meet the diverse needs of aging research applications. Our services include relative telomere length quantification, absolute telomere length quantification, average telomere length measurement, shortest telomere measurement, single-cell telomere length measurement, individual telomere length analysis, telomere length distribution measurement, and telomere length dynamic analysis.
With a strong focus on precision, reliability, and cutting-edge technology, we are dedicated to providing researchers with accurate and in-depth insights into telomere dynamics, contributing to the advancement of aging-related studies and the development of potential interventions.
Telomere Length Measurements in Various Samples
Our company provides telomere length measurement services for various species, including humans, non-human primates (NHPs), mice, Drosophila, and nematodes. Our services are tailored to meet the specific research needs of scientific investigations into aging processes across different organisms. To design and implement telomere length measurement protocols for different samples, we use information about the genomes of our study subjects. We provide our clients with detailed information on methods, results, and errors through graphical reports that demonstrate rigor, consistency, and clarity.
Sample types:
Sample volume:
> 5×106 cells, 15-30 mg chorionic villi, > 500 mg tissues
Notes:
Avoid freezing/thawing samples as it shortens the telomere length after sample collection.
NHP species:
Sample volume:
> 1 μg DNA, > 3 mL blood, > 2 ml saliva, > 5×106 cells, > 500 mg tissues
Notes:
Avoid freezing/thawing samples as it shortens the telomere length after sample collection.
Sample types:
Sample volume:
> 500 mg tissues, > 200 μL blood
Notes:
Avoid freezing/thawing samples as it shortens the telomere length after sample collection.
Sample types:
We can test a variety of Drosophila tissue samples such as the abdomen and wings.
Sample volume:
> 100 μg genomic DNA
Notes:
Sample requirements:
CD BioSciences emphasizes the collection of a substantial number of nematodes to achieve statistical significance. Proper sample preservation to prevent DNA degradation is also essential. We recommend fresh nematode samples as optimal.
Sample volume:
> 1 million cells or > 100 µg DNA
Analysis of Telomere Length Variations in Aging
Our tailored services encompass the development of telomere length as a robust biomarker of aging, in-depth analysis of the relationship between telomere length and various aging factors, and meticulous examination of the correlation between telomere length and age-related diseases. Our services highlight the intricate interplay between telomere length and aging factors, including but not limited to age, sex, and health risk factors, providing insights into how telomere length influences the aging process, age-related diseases, and overall health outcomes.
Analysis of Factors Associated with Telomere Length
We provide analyses of environmental, dietary, and behavioral factors that affect telomere length to explore the mechanisms that influence telomere shortening. By delving into the multifaceted relationship between lifestyle and environmental factors and telomere biology, we endeavor to broaden the understanding of aging processes and contribute to the development of evidence-based interventions aimed at promoting healthy aging.
We bring innovative technology to telomere length measurement and analysis for researchers and bioindustry companies.
| Technologies | Descriptions |
| Telomere measurement | We offer a range of telomere length measurements such as terminal restriction fragment (TRF), quantitative polymerase chain reaction (qPCR), and fluorescence in situ hybridization (FISH) techniques. |
| Aging animal model studies | We have classical animal models such as mice and fish for aging studies and validate telomere length-related impact factors through in vivo studies. |
CD BioSciences has extensive experience in providing biological research services, with a particular focus on telomere length analysis. Please contact us if you need any of these services or customize a special study.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
CD BioScience is a research service provider focused on aging research, specializing in providing research on aging mechanisms, preclinical drug discovery and development, and the development of healthcare and skincare products.
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