Subchronic and Chronic Toxicity Studies for Anti-Aging Drug Development

As the world's population ages, the demand for therapies that can mitigate the effects of aging has surged. However, the safety profile of these drugs is of paramount importance. Subchronic toxicity studies generally assess the effects of a substance after repeated exposure after 28 to 90 days, while chronic toxicity studies evaluate the long-term effects after long-term exposure, typically exceeding 90 days. These studies are crucial for identifying potential adverse effects associated with long-term drug use.

The potential for long-term use increases the risk of cumulative drug toxicity. CD BioSciences provides a range of subchronic and chronic toxicology studies to support the development of safe and effective anti-aging drugs. Our extensive experience in toxicity testing is instrumental in assessing whether new anti-aging therapeutics are both effective and safe for long-term use.

Our Subchronic and Chronic Toxicology Studies for Anti-Aging Drug Development

Subchronic toxicity testing

CD BioSciences offers subchronic toxicity testing for anti-aging drugs following rigorous procedures. Our experts administer the tested anti-aging drugs to appropriate animal models over a defined period of time to assess potential toxicological effects. We also help clients design routes of administration, dosage, and exposure duration. We monitor behavioral changes, body weight, food and water intake, and toxicity signs in animal modes. We also help clients evaluate hematological parameters, biochemical markers, and histopathological examinations of organs.

Chronic toxicity testing

CD BioSciences conducts chronic toxicity tests to evaluate the impact of long-term drug exposure. Our chronic toxicity test services always extend beyond 90 days. We employ advanced imaging and biomarker analysis techniques, ensuring a thorough evaluation of the chronic toxicity of anti-aging drugs. Our testing evaluates long-term effects on multiple organ systems, assessing renal function, liver enzymes, and neurological health. We also help clients assess drugs' potential to induce carcinogenicity, teratogenicity, or other long-term toxicities.

Addition Services

Dose-response analysis services

Understanding the dose-response relationship is critical for developing safe and effective anti-aging drugs. CD BioSciences provides detailed analyses that characterize the relationship between drug dose and the extent of its toxic effects. We help our clients optimize drug doses that maximize therapeutic benefits while minimizing adverse effects. We also help clients establish a no-observed adverse effect level (NOEL), which is the highest dose of an anti-aging drug at which no adverse effects are observed.

Target organ toxicity analysis services

CD BioSciences helps clients analyze the organs affected by subchronic and chronic exposure to anti-aging drugs. Our comprehensive services include detailed histopathological examinations and functional assays that can identify any organ-specific toxicity. By elucidating the target organ toxicity, we provide our clients with valuable insights that can guide further drug development and modification efforts.

The development of anti-aging drugs necessitates a rigorous safety evaluation, particularly through subchronic and chronic toxicity studies. At CD BioSciences, our commitment to scientific excellence and regulatory compliance enables us to offer comprehensive toxicity studies that meet clients' needs. If you are interested in our services, please feel free to contact us or make an online inquiry.