SU-5402
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SU-5402

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CAT. NO.: ABS-066

Product Details
Alternate Name 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid
CAS Number 215543-92-3
Molecular Formula C17H16N2O3
Molecular Weight 296.32
Appearance Yellow solid
Purity ≥97% by HPLC
Solubility DMSO (100 mM) )
SMILES CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O
PubChem CID 5289418
Handling Protect from air and light.
Storage Conditions -20°C
Description
A potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC50 = 0.03 µM for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC50 = 0.02 µM for VEGFR2). In addition, integrin β4-induced differentiation of neural stem cells was attenuated by SU 5402.

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