Smo Agonist, SAG
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Smo Agonist, SAG

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CAT. NO.: ABS-063

Product Details
Alternate Name N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane
CAS Number 912545-86-9
Molecular Formula C28H28ClN3OS
Molecular Weight 490.06
Appearance Off-white solid
Purity ≥98% by NMR
Solubility DMSO (>40 mg/mL)
Handling Protect from light.
Storage Conditions -20°C
Description
Cell-permeable. A Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.

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