CAT. NO.: ABU-007
| Product Details | |
|---|---|
| Alternate Name | 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one |
| CAS Number | 67200-34-4 |
| Molecular Formula | C11H4N4O2 |
| Molecular Weight | 224.18 |
| Appearance | Yellow solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>30 mg/mL) |
| SMILES | C1=CC=C2C(=C1)C3=NC4=NON=C4N=C3C2=O |
| PubChem CID | 568763 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| SMER-3 (Small molecule enhancer of rapamycin -3) is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes that results in cell cycle arrest and blockage of cell proliferation. | |
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