CAT. NO.: ABH-023
| Product Details | |
|---|---|
| Alternate Name | N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide |
| CAS Number | 287383-59-9 |
| Molecular Formula | C18H18N2O4 |
| Molecular Weight | 326.35 |
| Appearance | White to off-white solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (100 mM) |
| SMILES | C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCCCC(=O)NO |
| PubChem CID | 5186 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A relatively non-toxic Inhibitor of histone deacetylase (HDAC). Facilitates transcriptional activation (TGF-β/Smad4) in both stable and transient receptor assays in a concentration-dependent manner. At ~2 µg/mL (6-8 µM) concentrations, results in a greater than 100-fold increase in histone acetylation in PANC-1 cells. | |
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