SCAMP4 (E8Y6Z) Rabbit Antibody

INQUIRY

CAT. NO.: AMA-0168

Product Details
Size	100 μL
Reactivity	Human
Host	Rabbit
Source/Isotype	Rabbit IgG
Storage	Store at -20°C.
Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro30 of human SCAMP4 protein.

Usage
Application	WB
Product Usage Information Dilution	Western Blotting (1:1000)
MW (Target)	25 kDa

Background
Secretory carrier membrane proteins (SCAMPs) are a family of conserved integral membrane proteins localized to membranes of the cell-surface recycling system, including secretory organelles and endosomes. SCAMP1, SCAMP2, SCAMP3, and SCAMP4 are ubiquitously expressed, whereas SCAMP5 exhibits primarily neural expression. SCAMP4 protein is enriched on the surface of senescent cells, and its expression regulates the secretion of SASP (senescence-associated secretory phenotype) factors, including interleukin 6 (IL6), IL7, IL8, growth differentiation factor-15 (GDF-15), and C-X-C motif chemokine ligand 1 (CXCL1).

Background

Secretory carrier membrane proteins (SCAMPs) are a family of conserved integral membrane proteins localized to membranes of the cell-surface recycling system, including secretory organelles and endosomes. SCAMP1, SCAMP2, SCAMP3, and SCAMP4 are ubiquitously expressed, whereas SCAMP5 exhibits primarily neural expression.
SCAMP4 protein is enriched on the surface of senescent cells, and its expression regulates the secretion of SASP (senescence-associated secretory phenotype) factors, including interleukin 6 (IL6), IL7, IL8, growth differentiation factor-15 (GDF-15), and C-X-C motif chemokine ligand 1 (CXCL1).

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