CAT. NO.: ABH-022
| Product Details | |
|---|---|
| Alternate Name | Suberohydroxamic acid; suberic bis-hydroxamic acid; N,N'-dihydroxyoctanediamide |
| CAS Number | 38937-66-5 |
| Molecular Formula | C8H16N2O4 |
| Molecular Weight | 204.22 |
| Appearance | White to Off-white Solid |
| Purity | ≥95% by TLC |
| Solubility | H2O(100 mM) or DMSO (100 mM) |
| SMILES | C(CCCC(=O)NO)CCC(=O)NO |
| PubChem CID | 5173 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| SBHA is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM). SBHA causes cell differentiation, cell cycle arrest, or apoptosis. SBHA also enhances cytotoxicity induced by Oxaliplatin in the colorectal cancer cell lines. | |
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