RG 108
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RG 108

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CAT. NO.: ABS-060

Product Details
Alternate Name N-Phthalyl-L-tryptophan
CAS Number 48208-26-0
Molecular Formula C19H14N2O4
Molecular Weight 334.33
Appearance Beige to yelllow solid
Purity ≥98% by HPLC
Solubility DMSO (10 mg/mL)
SMILES C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
PubChem CID 702558
Handling Protect from air and moisture.
Storage Conditions -20°C
Description
A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG 108 enhances reprogramming.

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