Reversine
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Reversine

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CAT. NO.: ABS-059

Product Details
Alternate Name 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
CAS Number 656820-32-5
Molecular Formula C21H27N7O
Molecular Weight 393.49
Appearance Off-white solid
Purity ≥98% by TLC
Solubility DMSO (7-10 mg/mL)
SMILES C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
PubChem CID 210332
Handling Protect from air and light.
Storage Conditions -20°C
Description
A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66 μM) and an aurora kinase inhibitor (IC50's of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound.

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