CAT. NO.: ABM-017
| Product Details | |
|---|---|
| Alternate Name | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, AY 22989, Sirolimus |
| CAS Number | 53123-88-9 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.19 |
| Appearance | White to Off-white solid |
| Purity | ≥99% |
| Solubility | DMSO and EtOH |
| SMILES | CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC |
| PubChem CID | 5284616 |
| Handling | Protect from light and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| An immunosuppressant. Selectively blocks signaling that leads to p70 S6 kinase activation (IC50 = 50 pM). Inhibits lymphokine-induced cell proliferation at the G1 phase. Induces apoptosis in a murine B cell line. Rapamycin has been used in vivo studies by i.p., i.m., and i.v. administrations.. | |
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