CAT. NO.: AMA-0113
| Target Information | |
|---|---|
| UniProt ID | Q6MZQ0 |
| Product Details | |
|---|---|
| Size | 100 μL |
| Reactivity | Human, Monkey |
| Host | Rabbit |
| Source/Isotype | Rabbit IgG |
| Storage | Store at -20°C. |
| Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human protor-2 protein. |
| Usage | |
|---|---|
| Application | WB |
| Product Usage Information Dilution | Western Blotting (1:1000) |
| MW (Target) | 42 kDa |
| Background | |
|---|---|
| Protein observed with rictor-1 (protor-1) and protor-2 both interact with rictor and were identified as components of mTORC2. The absence of protor-1 or protor-2 does not affect the assembly of other mTORC2 components into an active complex. Protor-1 was shown to be essential for the activation of SGK1 mediated by mTORC2. Protor-2 plays a role in tristetraprolin-mediated mRNA turnover. | |
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