CAT. NO.: ABS-051
| Product Details | |
|---|---|
| Alternate Name | 9-Oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid; PGE2; Dinoprostone |
| CAS Number | 363-24-6 |
| Molecular Formula | C20H32O5 |
| Molecular Weight | 352.47 |
| Appearance | Crystalline solid |
| Purity | ≥98% by TLC |
| Solubility | DMSO (100 mg/mL) or EtOH (100 mg/mL) |
| SMILES | CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O |
| PubChem CID | 5280360 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Prostaglandin E2 (PGE2) is a primary product of arachidonic metabolism and is synthesized via the cyclooxygenase (COX) and prostaglandin synthase pathways. PGE2 production is a commonly used method for the detection of COX-1 and COX-2 modulation and prostaglandin synthases. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. Regulates vertebrate haematopoietic stem cell homeostasis. | |
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