PPP2R4 (5G3) Mouse Antibody

INQUIRY

CAT. NO.: AMA-0493

Target Information
UniProt ID	P58389

Product Details
Size	100 µL
Reactivity	Human, Mouse, Monkey
Host	Mouse
Source/Isotype	Mouse IgG2a
Storage	Store at -20°C. Do not aliquot the antibody.
Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the mouse PPP2R4 protein.

Usage
Application	WB
Product Usage Information Dilution	Western Blotting (1:1000)
MW (Target)	40 kDa

Background
Serine/threonine protein phosphatase 2A regulatory subunit 4 (PPP2R4) is one of the constituents of the regulatory subunit B' of PP2A PPP2R4 is also known as the phosphatase activator (PTPA) and known to have the peptidyl prolyl isomerase (PPIase) activity PPIases catalyze cis-trans isomerization of peptide bonds of proline residues in the polypeptide chain; this leads to the rapid folding of proteins The ATPase activity of PPP2R4 is required for the phosphotyrosyl phosphatase activity of PP2A Evidence suggests that PPP2R4 induces apoptosis independent of the canonical PP2A-mediated pathways.

Background

Serine/threonine protein phosphatase 2A regulatory subunit 4 (PPP2R4) is one of the constituents of the regulatory subunit B' of PP2A PPP2R4 is also known as the phosphatase activator (PTPA) and known to have the peptidyl prolyl isomerase (PPIase) activity PPIases catalyze cis-trans isomerization of peptide bonds of proline residues in the polypeptide chain; this leads to the rapid folding of proteins The ATPase activity of PPP2R4 is required for the phosphotyrosyl phosphatase activity of PP2A Evidence suggests that PPP2R4 induces apoptosis independent of the canonical PP2A-mediated pathways.

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