PP242

INQUIRY

CAT. NO.: ABM-015

Product Details
Alternate Name	2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
CAS Number	1092351-67-1
Molecular Formula	C₁₆H₁₆N₆O
Molecular Weight	308.34
Appearance	White to off-white solid
Purity	≥98% by HPLC
Solubility	DMSO (>50 mg/mL)
SMILES	CC(C)N1C2=C(C(=C3C=C4C=C(C=CC4=N3)O)N1)C(=NC=N2)N
PubChem CID	25243800
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC50 = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin.

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