PI3 Kinase Class III (D9A5) Rabbit Antibody
Online Inquiry

PI3 Kinase Class III (D9A5) Rabbit Antibody

INQUIRY

CAT. NO.: AMA-0680

Target Information
UniProt ID Q8NEB9
Product Details
Size 100 µL
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Source/Isotype Rabbit IgG
Storage Store at -20°C. Do not aliquot the antibody.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide surrounding Lys630 of human PI3 kinase class III.
Usage
Application WB, IP
Product Usage Information Dilution Western Blotting (1:1000); Immunoprecipitation (1:50)
MW (Target) 100 kDa
Background
Three distinct types of phosphoinositide 3-kinases (PI3K) have been characterized. Unlike other PI3Ks, PI3K class III catalyzes the phosphorylation of phosphatidylinositol at the D3 position, producing phosphatidylinositol-3-phosphate (PIP3) PI3K class III is the mammalian homolog of Vps34, first identified in yeast. PI3K class III interacts with the regular subunit p150, the mammalian homolog of Vps15, which regulates cellular membrane association through myristoylation PIP3 recruits several proteins with FYVE or PX domains to membranes regulating vesicular transport and protein sorting Moreover, PI3K class III has been shown to regulate autophagy, trimeric G-protein signaling, and the mTOR nutrient-sensing pathway.

Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our products, please contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.