CAT. NO.: ABM-014
| Product Details | |
|---|---|
| Alternate Name | 2-amino-8-((1r,4r)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one |
| CAS Number | 1013101-36-4 |
| Molecular Formula | C22H27N5O4 |
| Molecular Weight | 425.48 |
| Appearance | Crystalline solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>10 mg/mL) |
| SMILES | CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC |
| PubChem CID | 25033539 |
| Handling | Protect from light and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A potent, ATP-competitive PI3K/mTOR dual inhibitor with broad antitumor activity. PF-04691502 potently inhibits recombinant class I PI3K and mTOR in biochemical assays and suppresses transformation of avian fibroblasts mediated by wild-type PI3K γ, δ, or mutant PI3Kα. | |
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