CAT. NO.: AMA-0053
| Target Information | |
|---|---|
| UniProt ID | O15530 |
| Product Details | |
|---|---|
| Size | 20 μL/100 μL |
| Reactivity | Human, Monkey, Mouse, Rat |
| Storage | Store at -20°C. |
| Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the carboxy terminus of human PDK1. Antibodies are purified by protein A and peptide affinity chromatography. |
| Usage | |
|---|---|
| Application | WB |
| Product Usage Information Dilution | Western Blotting (1:1000) |
| MW (Target) | 58-68 kDa |
| Background | |
|---|---|
| Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis. | |
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