CAT. NO.: ABS-047
Product Details | |
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Alternate Name | CI-1040 |
CAS Number | 212631-79-3 |
Molecular Formula | C17H14ClF2IN2O2 |
Molecular Weight | 478.67 |
Appearance | Crystalline solid |
Purity | ≥99% by HPLC |
Solubility | DMSO (600 mg/mL) |
SMILES | C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl |
PubChem CID | 6918454 |
Handling | Protect from light and moisture. |
Storage Conditions | -20°C |
Description | |
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A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC50 of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5. |
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