PD184352
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PD184352

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CAT. NO.: ABS-047

Product Details
Alternate Name CI-1040
CAS Number 212631-79-3
Molecular Formula C17H14ClF2IN2O2
Molecular Weight 478.67
Appearance Crystalline solid
Purity ≥99% by HPLC
Solubility DMSO (600 mg/mL)
SMILES C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
PubChem CID 6918454
Handling Protect from light and moisture.
Storage Conditions -20°C
Description
A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC50 of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.

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