Oxamflatin
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Oxamflatin

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CAT. NO.: ABH-015

Product Details
Alternate Name N-​hydroxy-​5-​[3-​[(phenylsulfonyl)amino]phenyl]-​2E-​penten-​4-​ynamide; Metacept 3
CAS Number 151720-43-3
Molecular Formula C17H14N2O4S
Molecular Weight 342.37
Appearance White to Off-white Solid
Purity ≥95%
Solubility DMSO (5 mg/mL) or EtOH (0.5 mg/mL)
SMILES C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C#CC=CC(=O)NO
PubChem CID 5353852
Handling Protect from light and moisture.
Storage Conditions -20°C
Description
A potent inhibitor of mammalian histone deacetylases (HDACs) (IC50 = 15.7 nM). A novel antitumor agent; oxamflatin modifies epigenetic status and gene expression, increases blastocyst quality, and subsequently enhances the nuclear reprogramming and developmental potential of SCNT (somatic cell nuclear transfer) embryos.

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