CAT. NO.: ABM-012
| Product Details | |
|---|---|
| Alternate Name | 4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid; ASP4786 |
| CAS Number | 936890-98-1 |
| Molecular Formula | C21H22N6O3 |
| Molecular Weight | 406.44 |
| Appearance | Crystalline solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (18 mg/mL) |
| SMILES | COC1=CC=CC2=CC(=C3C4=C(N=CNN4C(=N3)C5CCC(CC5)C(=O)O)N)N=C21 |
| PubChem CID | 44224160 |
| Handling | Protect from light and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| OSI-027 is a potent mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. It binds to and inhibits both the raptor-mTOR (TOR complex 1 or TORC1) and the rictor-mTOR (TOR complex 2 or TORC2) complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. | |
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