CAT. NO.: ABU-004
| Product Details | |
|---|---|
| Alternate Name | 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol |
| CAS Number | 6964-62-1 |
| Molecular Formula | C23H20N2O |
| Molecular Weight | 340.42 |
| Appearance | White solid |
| Purity | ≥97% by HPLC |
| Solubility | DMSO (100 mM) |
| SMILES | CC1=NC2=C(C=C1)C=CC(=C2O)C(C3=CC=CC=C3)NC4=CC=CC=C4 |
| PubChem CID | 248986 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Cell-permeable. Potent MDM2 (murine double minute 2) inhibitor (Ki = 120 nM) that disrupts MDM2-p53 interaction and activates p53 in cancer cells. Induces p21, p53 and MDM2 accumulation in human colon cancer cells in vitro. | |
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