CAT. NO.: AMA-0454
| Target Information | |
|---|---|
| UniProt ID | P29477 |
| Product Details | |
|---|---|
| Size | 100 µL |
| Reactivity | Human, Mouse |
| Storage | Store at -20°C. Do not aliquot the antibody. |
| Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide surrounding Ser1000 of human iNOS. Antibodies are purified by protein A and peptide affinity chromatography. |
| Usage | |
|---|---|
| Application | WB |
| Product Usage Information Dilution | Western Blotting (1:1000) |
| MW (Target) | 130 kDa |
| Background | |
|---|---|
| Nitric Oxide Synthase (NOS) catalyzes the formation of nitric oxide (NO) and citrulline from L-arginine, oxygen, and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels NO is a messenger molecule with diverse functions throughout the body, including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory. | |
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