Naringenin

INQUIRY

CAT. NO.: ABA-032

Product Details
Alternate Name	5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; NGEN
CAS Number	480-41-1
Molecular Formula	C₁₅H₁₂O₅
Molecular Weight	272.26
Appearance	Brown solid
Purity	≥98% by TLC
Solubility	DMSO or EtOH (50 mg/mL)
SMILES	C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
PubChem CID	932
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
The major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet. Also lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed with a high-cholesterol diet.

Description

The major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet. Also lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed with a high-cholesterol diet.

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