CAT. NO.: ABM-011
| Product Details | |
|---|---|
| Alternate Name | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
| CAS Number | 1062172-60-4 |
| Molecular Formula | C30H34N8O5 |
| Molecular Weight | 586.64 |
| Appearance | White solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (>60 mg/mL) |
| SMILES | COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)NC(=O)NC5=CC=C(C=C5)CO)N6CCOCC6 |
| PubChem CID | 24936050 |
| Handling | Protect from light and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian Target Of Rapamycin) inhibitor (IC50 = 0.08 nM). Displays 75-fold selectivity over PI3Kα (IC50 = 6 nM). | |
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