mTOR Inhibitor, Ku-0063794
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mTOR Inhibitor, Ku-0063794

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CAT. NO.: ABM-008

Product Details
Alternate Name rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
CAS Number 938440-64-3
Molecular Formula C25H31N5O4
Molecular Weight 465.54
Appearance Pale yellow solid
Purity ≥98% by HPLC
Solubility DMSO
SMILES CC1CN(CC(O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5
PubChem CID 16736978
Handling Protect from air and light.
Storage Conditions -20°C
Description
A potent mTOR (mammalian target of rapamycin) inhibitor (IC50 = ~10 nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.

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