CAT. NO.: ABS-040
| Product Details | |
|---|---|
| Alternate Name | (2E)-N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-2-propenamide; CID-50910523 |
| CAS Number | 1426576-80-8 |
| Molecular Formula | C14Hv16N2OS |
| Molecular Weight | 260.35 |
| Appearance | White solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (5 mg/mL) |
| SMILES | CCC1=CC=C(C=C1)C=CC(=O)NC2=NCCS2 |
| PubChem CID | 50910523 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC₅₀ = 2.0 µM) over a control (mammary epithelial) cell line (EC₅₀ = 64 µM). It weakly antagonizes the adenosine A2A receptor (IC50 = 10 µM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling. | |
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