Mek1/2 Antibody
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Mek1/2 Antibody

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CAT. NO.: AMA-0218

Product Details
Size 100 μL
Reactivity Human, Mouse, Rat
Host Rabbit
Source/Isotype Rabbit IgG
Storage Store at -20°C.
Purification Affinity purified
Usage
Application WB
Product Usage Information Dilution Western Blotting (1:500-1000)
Background
MAP kinase kinase 1 (Mek1), also known as mitogen activated protein kinase kinase, MAP kinase kinase, ERK kinase 1 or microtubule-associated protein 2 kinase, is a 43 kDa dual-specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine-threonine kinase, Raf-1, which is part of the p21ras signal transduction pathway.

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