CAT. NO.: ABA-026
| Product Details | |
|---|---|
| Alternate Name | N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
| CAS Number | 950455-15-9 |
| Molecular Formula | C19H21ClN4 |
| Molecular Weight | 340.85 |
| Appearance | White to off-white solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (10 mg/mL) |
| SMILES | C1CNCCC12C(=NC3=CC=CC=C3N2)NCC4=CC(=CC=C4)Cl |
| PubChem CID | 20931416 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice. Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice. | |
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