LAMTOR3/MAPKSP1 (D38G5) Rabbit Antibody
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LAMTOR3/MAPKSP1 (D38G5) Rabbit Antibody

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CAT. NO.: AMA-0649

Target Information
UniProt ID Q9UHA4
Product Details
Size 100 µL
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Source/Isotype Rabbit IgG
Storage Store at -20°C. Do not aliquot the antibody.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val16 of human LAMTOR3/MAPKSP1 protein.
Usage
Application WB
Product Usage Information Dilution Western Blotting (1:1000)
MW (Target) 14 kDa
Background
mTORC1 kinase complex is a critical component in the regulation of cell growth Its activity is modulated by energy levels, growth factors, and amino acids The four related GTPases, RagA, RagB, RagC, and RagD, have been shown to interact with raptor in mTORC1 These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals A protein complex consisting of LAMTOR1/C11orf59, LAMTOR2/ROBLD3, and LAMTOR3/MAPKSP1 has been identified to interact with and recruit the four Rag GTPases to the surface of lysosomes.

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