Jak1 (6G4) Rabbit Antibody (BSA and Azide Free)
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Jak1 (6G4) Rabbit Antibody (BSA and Azide Free)

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CAT. NO.: AMA-0567

Target Information
UniProt ID P23458
Product Details
Size 100 µg
Reactivity Human, Mouse, Rat
Host Rabbit
Source/Isotype Rabbit IgG
Storage Store at -20°C. Do not aliquot the antibody.
Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile800 of Jak1.
Usage
Application WB, IHC
MW (Target) 130 kDa
Background
Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats Shc insulin receptor substrates and focal adhesion kinase (FAK) typically contain SH2 or other phospho-tyrosine-binding domains.

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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.