IQ-1
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IQ-1

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CAT. NO.: ABS-030

Product Details
Alternate Name 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
CAS Number 331001-62-8
Molecular Formula C21H22N4O2
Molecular Weight 362.42
Appearance Orange solid
Purity ≥95% by HPLC
Solubility DMSO
SMILES CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
PubChem CID 11152734
Handling Protect from air and light.
Storage Conditions 4°C
Description
Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.

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