CAT. NO.: ABS-030
Product Details | |
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Alternate Name | 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide |
CAS Number | 331001-62-8 |
Molecular Formula | C21H22N4O2 |
Molecular Weight | 362.42 |
Appearance | Orange solid |
Purity | ≥95% by HPLC |
Solubility | DMSO |
SMILES | CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N |
PubChem CID | 11152734 |
Handling | Protect from air and light. |
Storage Conditions | 4°C |
Description | |
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Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency. |
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