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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Integrin α5 (D7B7G) Rabbit Antibody

INQUIRY

CAT. NO.: AMA-0603

Target Information
UniProt ID	P08648

Product Details
Size	100 µL
Reactivity	Human, Mouse, Rat, Hamster, Monkey
Host	Rabbit
Source/Isotype	Rabbit IgG
Storage	Store at -20°C. Do not aliquot the antibody.
Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly117 of human Integrin α5 protein.

Usage
Application	WB
Product Usage Information Dilution	Western Blotting (1:1000)
MW (Target)	150 kDa

Background
Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling)Integrin α5/β1 is involved in multiple biological processes including embryonic development, angiogenesis and tumor metastasis By interaction with its fibronectin ligand, α5/β1 transduces signals that regulate cell adhesion, migration, matrix assembly and cytoskeletal organization.

Background

Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling)Integrin α5/β1 is involved in multiple biological processes including embryonic development, angiogenesis and tumor metastasis By interaction with its fibronectin ligand, α5/β1 transduces signals that regulate cell adhesion, migration, matrix assembly and cytoskeletal organization.

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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.