Inflammaging Analysis Services

Inflammaging, a term combining "inflammation" and "aging," refers to the chronic, low-grade inflammation that accompanies the aging process. It is characterized by an increased production of pro-inflammatory molecules and a dysregulated immune response. Recognized increasingly as a key contributor to age-related diseases, inflammaging has become a significant focus within the field of biogerontology.

Fig. 1 Inflammageing is a risk factor for multiple chronic diseases. (Ferrucci L and Fabbri E, 2018)

Understanding the mechanisms that underlie inflammaging is essential in developing targeted interventions that promote healthy aging. CD BioSciences offers an array of state-of-the-art techniques to unravel the complexities of inflammaging, providing our clients with valuable aging-related insights.

Overview of Our Inflammaging Analysis Services

Inflammaging biomarker analysis

We provide cutting-edge methods to detect and measure biomarkers of inflammaging, spanning a broad spectrum of molecular indicators linked to chronic inflammation during aging. Our services include a comprehensive exploration of biomarkers associated with inflammaging, including C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and more. Our team employs advanced approaches across proteomics, genomics, and metabolomics to detect and measure crucial biomolecules implicated in the inflammatory response.

Inflammaging profiling

Our scientific team utilizes genomic sequencing technologies to analyze gene expression patterns, epigenetic modifications, and genetic variations associated with inflammaging. By integrating multi-omics data, we can create detailed profiles that capture the intricate interplay between genetic and environmental factors contributing to inflammaging.

In addition to genomics, our profiling services include comprehensive analysis of cytokine and chemokine levels, immune cell populations, and tissue-specific inflammatory responses. Our detailed profiles provide valuable insights into the complex network of molecular and cellular interactions involved in inflammaging.

Inflammaging research and development

We help our clients research the mechanisms and pathways in inflammaging to develop potential interventions or therapeutics. We study the interactions between the immune system, inflammatory mediators, and aging-related physiological changes. Our services aim to identify specific targets within the inflammatory pathways that can be modulated to attenuate or counteract the effects of inflammaging.

Our Workflow of Analyzing Inflammaging in Aging Studies

We choose individuals without substantial ongoing acute inflammation that may affect the analysis of inflammaging. Afterward, we gather biological specimens, such as blood, tissues, or other pertinent materials, for inflammaging analysis. We perform inflammaging biomarker analysis and profiling as described previously.

We analyze the collected data to identify patterns, correlations, and potential connections between inflammatory markers and age-related factors. We offer a thorough analysis of the data, which includes identifying pathways, annotating functionality, and detecting critical regulatory networks linked to inflammaging. Ultimately, we provide comprehensive reports that summarize the results of the analysis, including detailed methodologies, outcomes, and interpretations.

Our Advantages

• Based on our extensive experience, we possess a thorough comprehension of immunological processes related to aging. We gain insight into the alterations in immune function and inflammatory responses that arise during aging.
• We possess the capability to examine a broad spectrum of biomarkers linked to inflammation, such as cytokines, chemokines, acute-phase proteins, and cellular markers. Our proficiency allows for a comprehensive profiling of the inflammatory processes that occur during aging.
• We offer tailored solutions that accommodate the specific needs of our clients. Whether it's a focus on biomarker identification or comprehensive profiling, our customized approach ensures that we address the unique requirements of each study with precision and efficiency.

CD BioSciences offers thorough analysis services for inflammaging, utilizing advanced technologies, a systematic workflow, and a cooperative approach. If you are interested in our services, please feel free to contact us or make an online inquiry.

Reference

1. Ferrucci L, Fabbri E. Inflammageing: chronic inflammation in aging, cardiovascular disease, and frailty. Nat Rev Cardiol. 2018, 15 (9): 505-522.