In Vitro Toxicity Testing Services for Anti-Aging Drug Development

In the anti-aging drug development process, in vitro toxicity testing is a critical step in evaluating the potential adverse effects of new compounds. These tests provide a controlled environment to assess drug toxicity without the use of animal models, offering a cost-effective and ethically favorable approach. It allows for the early identification of potentially toxic drugs, saving time and resources.

CD BioSciences specializes in providing comprehensive in vitro toxicity testing services with a focus on the unique requirements of anti-aging drugs. Our commitment to scientific excellence, combined with our advanced testing capabilities, ensures that our clients receive high-quality data to support their drug development efforts.

Overview of Our In Vitro Toxicity Testing Services for Anti-Aging Drug Development

Dermal toxicity testing

We offer dermal toxicity testing to assess the effects of anti-aging drugs when applied to the skin. We employ reconstructed human epidermis (RhE) models, which closely mimic the structure and function of human skin. Our services allow for assessing skin irritation, corrosion, and sensitization. Additionally, we help clients analyze the impact of anti-aging drugs on cell health. We also evaluate the potential cytotoxic effects of drugs on keratinocytes and fibroblasts, which are essential for skin health.

Ocular irritation testing

Our in vitro ocular irritation testing uses reconstructed human cornea-like epidermis (RhCE) models to evaluate the potential for irritation or damage to the eye. After treatment with the tested anti-aging drugs, we help clients determine the relative viability by photometrically measuring the formazan produced by enzymatic reduction of MTT. Our services are also available for anti-aging drugs that may be applied near the eye region. We provide reliable data to help clients assess whether anti-aging drugs are safe.

Phototoxicity testing

We offer phototoxicity testing to evaluate the potential for anti-aging drugs to cause adverse effects when exposed to light, particularly ultraviolet (UV) radiation. Our scientists can help clients design specific exposure conditions and customized light source configurations. We examine damage signs of samples following phototoxic exposure, such as cellular apoptosis or necrosis, providing a comprehensive view of the effects of anti-aging drugs. We also help measure the levels of reactive oxygen species (ROS) generated in cells exposed to the anti-aging drugs under light. Elevated ROS levels can indicate phototoxic potential.

Why Choose Us?

• Expertise. Our team is comprised of experienced scientists with a deep understanding of in vitro toxicology and anti-aging drug development. We offer tailored testing protocols to meet the specific requirements of each drug candidate.
• Well-established in vitro models. We use well-established human cell lines to test specific adverse pathways, enhancing the predictive accuracy of human responses.
• Biochemical screening assays. We are proficient in screening for key biochemical and biomarker endpoints of toxicity.
• Comprehensive toxicity testing. We use multiple assays in a complementary manner to provide a holistic assessment of toxicity, enhancing the robustness of results.

At CD BioSciences, our in vitro toxicity testing services for anti-aging drug development provide a foundation for safety assessment. We are a reliable partner of pharmaceutical companies seeking to advance safe and effective anti-aging therapeutics. If you are interested in our services, please feel free to contact us or make an online inquiry.