Human recombinant Thioredoxin
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Human recombinant Thioredoxin

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CAT. NO.: APE-036

Product Details
Size 100 μg
Alternate Name TXN, TRX, TRX1
Gene Symbol TXN
Gene ID 7295
Source E. coli
Appearance Liquid
Physical Form Description 1 mg/mL solution in PBS (pH 7.4).
Molecular Weight 11.7 kDa
Purity by SDS-PAGE ≥95%
Amino Acid Sequence MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Description
Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques.

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