CAT. NO.: APE-036
| Product Details | |
|---|---|
| Size | 100 μg |
| Alternate Name | TXN, TRX, TRX1 |
| Gene Symbol | TXN |
| Gene ID | 7295 |
| Source | E. coli |
| Appearance | Liquid |
| Physical Form Description | 1 mg/mL solution in PBS (pH 7.4). |
| Molecular Weight | 11.7 kDa |
| Purity by SDS-PAGE | ≥95% |
| Amino Acid Sequence | MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques. | |
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