GSK-3β Inhibitor, TWS119
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GSK-3β Inhibitor, TWS119

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CAT. NO.: ABS-021

Product Details
Alternate Name 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol
CAS Number 601514-19-6
Molecular Formula C18H14N4O2
Molecular Weight 318.33
Appearance Slightly pink solid
Purity ≥95% by HPLC
Solubility DMSO (20 mg/mL)
SMILES C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O
PubChem CID 9549289
Handling Protect from air and light.
Storage Conditions -20°C
Description
A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (IC50 = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.

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