CAT. NO.: ABS-021
Product Details | |
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Alternate Name | 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol |
CAS Number | 601514-19-6 |
Molecular Formula | C18H14N4O2 |
Molecular Weight | 318.33 |
Appearance | Slightly pink solid |
Purity | ≥95% by HPLC |
Solubility | DMSO (20 mg/mL) |
SMILES | C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O |
PubChem CID | 9549289 |
Handling | Protect from air and light. |
Storage Conditions | -20°C |
Description | |
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A potent inhibitor of GSK-3β (Glycogen synthase kinase-3β) (IC50 = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. |
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