The quest for anti-aging therapies has received significant attention in recent years, driven by increasing consumer demand for longevity and enhanced quality of life. Genetic toxicology plays a critical role in this process by assessing the ability of a drug to induce genetic damage that could lead to carcinogenesis or other adverse effects. Regulatory agencies require that all new drugs undergo rigorous genetic toxicology evaluations.
CD BioSciences is a reliable provider of comprehensive genetic toxicology services, offering both in vitro and in vivo assessments to support the development of safe and effective anti-aging drugs.
The Ames test, the cornerstone of genetic toxicology testing, is designed to assess the mutagenic potential of drugs. We use non-pathogenic bacterial strains, typically Salmonella typhimurium, to evaluate whether the tested anti-aging drug induces mutations in the DNA. By identifying mutagenic properties early in the development process, CD BioSciences helps clients evaluate the safety of anti-aging drugs.
We offer in vitro micronucleus test to help clients determine whether anti-aging drugs induce micronuclei formation in cultured cells, which indicates chromosomal damage. Our experts utilize advanced cell culture techniques, imaging systems, and analysis software to ensure reliable results, providing our clients with reliable results.
We provide in vitro chromosomal aberration tests to evaluate the potential of anti-aging drugs to cause structural chromosomal aberrations. We help clients assess chromosomal integrity after exposure to anti-aging drugs. We offer expert cytogenetic analysis to identify and classify different types of chromosomal aberrations.
We offer in vitro gene mutation tests to help clients assess the ability of anti-aging drugs to induce mutations in specific genes. Our experts help clients test specific gene mutations known to be sensitive to mutagens, such as the TK and HPRT genes. We conduct these tests using specialized cell lines to ensure a comprehensive assessment and reliable data.
CD BioSciences offers in vivo rodent micronucleus tests to complement in vitro findings. Our experts help clients administer anti-aging drugs to rodents and subsequently analyze their bone marrow for micronuclei formation. We help clients collect samples, prepare experiments, perform assays, and analyze data.
We help clients determine chromosomal aberrations in rodents treated with anti-aging drugs. We offer detailed histopathological examination of tissues to detect and characterize chromosomal damage. We have expertise in collecting biological samples and using advanced cytogenetic techniques to analyze chromosomal integrity.
By evaluating the extent of DNA strand breaks in treated mammalian models, we can assess the genotoxic potential of anti-aging drugs. We assist clients in separating cells from various tissues for analysis.
The development of anti-aging drugs presents unique challenges, particularly in terms of genetic safety. CD BioSciences enables clients to identify potential genetic risks associated with anti-aging drugs through our comprehensive genetic toxicology services. If you are interested in our services, please feel free to contact us or make an online inquiry.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
CD BioScience is a research service provider focused on aging research, specializing in providing research on aging mechanisms, preclinical drug discovery and development, and the development of healthcare and skincare products.
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