CAT. NO.: ABS-019
| Product Details | |
|---|---|
| Alternate Name | 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691 |
| CAS Number | 879085-55-9 |
| Molecular Formula | C19H14Cl2N2O3S |
| Molecular Weight | 421.3 |
| Appearance | White to off-white solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (200 mg/mL) or EtOH (10 mg/mL with warming) |
| SMILES | CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl |
| PubChem CID | 24776445 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth. | |
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