CAT. NO.: APE-021
| Product Details | |
|---|---|
| Size | 10 μg |
| Alternate Name | Fat Mass and Obesity-associated Protein; FATSO. |
| Gene Symbol | FTO |
| Gene ID | 26383 |
| Source | E. coli |
| Appearance | Liquid |
| Physical Form Description | 0.5 mg/mL of 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl. |
| Molecular Weight | 55 kDa |
| Purity by SDS-PAGE | ≥90% |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. | |
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