Fish Telomerase Protein Component 1 (TEP1) ELISA Kit

INQUIRY

CAT. NO.: TK026

General Info
Size	48-Strip-Wells / 96-Strip-Wells / 5×96-Strip-Wells / 10×96-Strip-Wells
Product Overview	This product constitutes a ready-to-use microwell and strip plate ELISA (enzyme-linked immunosorbent assay) Kit designed for the assessment of the Telomerase Protein Component 1 (TEP1) ELISA Kit target analytes within biological samples. The concentration gradients of the Kit standards or positive controls render a theoretical Kit detection range in biological research samples containing TEP1. The ELISA analytical biochemical technique of the Kit is based on TEP1 antibody-TEP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TEP1 antigen targets in samples. It's important to note that this ELISA Kit is specifically tailored for detecting native, not recombinant TEP1.
Storage Conditions	Store all reagents at 2-8°C
Notes	Occasionally, trace amounts of reagent may remain in the closure of the product vial during shipment and storage of the TEP1 ELISA kit. It is recommended that any liquid that may be present in the lid of the container be centrifuged to the bottom using a bench-top centrifuge prior to experimentation.
Reactivity	Fish
Shipping Conditions	Dry Ice

Product Details
Samples	Undiluted Body Fluids, Tissue Homogenates, Secretions

Target Info
Molecular Weight	289,578 Da
NCBI Accession	NP_009041.2
NCBI GenBank Nucleotide	NM_007110.4
NCBI GeneID	7011
NCBI Official Full Name	telomerase protein component 1 isoform 1
NCBI Official Symbol	TEP1
NCBI Official Synonym Full Names	telomerase associated protein 1
NCBI Official Synonym Symbols	TP1, TLP1, p240, TROVE1, VAULT2
NCBI Protein Information	telomerase protein component 1
OMIM	601686
UniProt Entry Name	TEP1_HUMAN
UniProt Gene Name	TEP1
UniProt Protein Name	Telomerase protein component 1
UniProt Synonym Gene Names	TLP1, TP1, Telomerase protein 1
UniProt Synonym Protein Names	Telomerase-associated protein 1, Telomerase protein 1, p240, p80 telomerase homolog
UniProt Primary Accession	Q99973
UniProt Secondary Accession	A0AUV9
Protein Family	Telomerase protein component
NCBI Summary	This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Comments	TEP1: Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi- subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA repair, damageChromosomal Location of Human Ortholog: 14q11.2Cellular Component: chromosome, telomeric region; cytoplasm; nuclear matrix; ribonucleoprotein complex; telomerase holoenzyme complexMolecular ATP binding; enzyme binding; p53 binding; RNA binding; telomerase activityBiological Process: RNA-dependent DNA replication; telomere maintenance via recombination

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